This data refers to:

Concomitant AD and DLB pathologies shape subfield microglia responses in the hippocampus
https://www.biorxiv.org/content/10.1101/2022.01.06.475218v1
Corresponding author: david.bouvier@lns.etat.lu

The data is organized as follows:

a) Example for MIC-MAC 2 segmentation : contains only three images and the relative parameters to execute the image segmentation step.

b) Data : contains all the data acquired and generated throughout the computational steps presented in the manuscript. More specifically:
	- 1 Raw microglia : contains all the raw acquisitions.
	- 2 Segmented microglia : contains all the MIC-MAC 2 segmentations in TIF format
	- 3 Feature Extraction microglia : contains two type of files per sample :
		~ attributes : a MatLab file including cell morphological features values
		~ volumes : a MatLab file including the 3D volumetric morphologies
	- 4 Neuropathology :
		- contains raw and segmented images and quantitative analysis of amyloid beta, P-Tau and P-Syn staining
		- contains raw images for colocalisation of P-Syn P-Tau with various antibodies
		- contains raw images for P-Syn antibody validation with various antibodies
		- contains raw image for definition of hippocampal subregions
	- 5 Analysis : contains all the merged information used for the statistics and visualization
	- Metadata : contains information regarding the samples and parameters used during the segmentation phase
	- Overlays : contains Imaris overlays of the raw data and the MIC-MAC 2 segmentations