This application stops the analysis process at the gene modules identification and relation with clinical variables.

The next step in interpreting the results would be to submit modules correlated with a clinical trait of interest to an enrichment analysis tool, in order to explore the biological meaning of said modules.

This can be done by exporting the modules definitions (by clicking on the Download module assignments button at the end of section 2) and uploading each module to the user’s favourite enrichment software. Usual choices include MetaCore, Ingenuity Pathway Analysis, g:Profiler or DAVID, among others.

A clearer picture of the molecular mechanisms involved in the correlation with a clinical trait can be obtained by collating enrichment analysis results from all modules correlated with said clinical trait.